Renewable Chemical Innovator Capra Biosciences Raises $1.8M in Oversubscribed Pre-Seed Round

June 6, 2022

Manassas, VA – June 6, 2022: Capra Biosciences today announced it has raised $1.8M in an oversubscribed pre-seed funding round to advance their continuous-flow bioreactor technology, which changes the economics of making sustainable petrochemical replacements using biology. Capra will use the funding to build their production-scale reactor and extend its capabilities to include the production of lubricants.

The company works at the intersection of biology and hardware engineering to build a new kind of continuous flow bioreactor that leverages the unique features of their platform organism. Capra Biosciences emerged from the competitive IndieBio program backed by SOSV. Pre-Seed investors include Prithvi Ventures, the E14 Fund, GS Futures, Antimo’s president – Wes Osbourn, Savantus Ventures, Asymmetry Ventures, the Decarbonization Consortium, and SOSV, among others.

The company works at the intersection of biology and hardware engineering to build a new kind of continuous flow bioreactor that leverages the unique features of their platform organism. “Reaching this funding milestone is important because our production-scale reactor is modular. Much like a data center’s capacity grows as it adds individual hard drives, our platform’s ability to produce chemicals at scale grows with each bioreactor we add,” said Dr. Andrew Magyar, Capra’s chief technology officer. “This enables us to avoid many of the scale-up challenges experienced in traditional bioreactors. The funding allows us to move quickly into our production scale bioreactor.”

Capra’s first product is retinol, a highly lucrative cosmetic ingredient used in anti-aging products.

Capra’s novel approach to retinol production uses biology rather than fossil fuels for production, unlike other products currently on the market.

The company is also pursuing several aviation and industrial lubricants for future production phases. Like retinol, the $150B lubricant market is closely linked to petrochemicals. Capra is breaking the link to fossil fuels and providing a cleaner, more sustainable path for lubricant production. The company makes renewable products using sources of carbon that don’t compete with food sources or divert undeveloped land towards agricultural production.

“Even most climate-focused VCs haven’t thought about the massive, $150B lubricants market. But they should. 20% of the world’s energy is spent overcoming friction,” said Po Bronson, Managing Director of IndieBio and General Partner at SOSV. “All motors and all moving parts need lubricants – from robots to spacecraft, to machines and elevators. The secret is that biology can make sophisticated compounds that petroleum chemistry cannot, enabling performance characteristics that make machines last longer.”

“Equally important is how Capra produces their products. Capra’s bioreactor can truly disrupt the very economics of fermentation bioreactors,” said Pae Wu, CTO at IndieBio and General Partner at SOSV. “The current infrastructure for fermentation involves huge and expensive steel tanks that mostly hold water. Capra’s system grows microorganisms with very little water, shrinking the size-to-output ratio by as much as 100x. And it’s made from low-cost materials.”

Capra’s founder, Dr. Elizabeth Onderko, invented the company’s bioreactor technology as a postdoctoral associate at the U.S. Naval Research Laboratory (NRL) along with her advisor Dr. Sarah Glaven, federal employee Dr. Matthew Yates, and Capra’s co-founder and CTO, Dr. Andrew Magyar. The Capra team continues to support the development of this technology to address Department of Defense needs through a cooperative research and development agreement (CRADA). “This partnership is a prime example for how fundamental research can be developed, matured, and successfully transitioned from NRL benchtop to commercial partner. The Technology Transfer Office often facilitates these types of efforts through various mechanisms which aim to incentivize businesses and bring forth investment capital,” said Dr. Stephen Deese, NRL Partnership Manager.

“We’re excited to make products that create a positive impact on the world, while simultaneously reducing carbon emissions,” said Capra co-founder and CEO, Dr. Elizabeth Onderko. “Our production scale reactor empowers us to place samples of retinol, Capra’s first product, into customers hands for evaluation – our first step to decarbonizing the chemical industry. Next up we’re developing sustainable, high performance lubricants and many other chemical products – allowing us to start reducing the more than three gigatons of greenhouse gas emissions from chemical manufacturing. The potential for our technology is massive, and we’re very thankful to our investors for sharing in our vision.”

About Capra Biosciences

Capra Biosciences is venture-backed startup company focused on sustainable production of petrochemical replacements using their biofilm bioreactor platform. Capra Biosciences is located in Manassas, VA. To learn more about the company, visit

About the U.S. Naval Research Laboratory

NRL is a scientific and engineering command dedicated to research that drives innovative advances for the U.S. Navy and Marine Corps from the seafloor to space and in the information domain. NRL is located in Washington, D.C. with major field sites in Stennis Space Center, Mississippi; Key West, Florida; Monterey, California, and employs approximately 3,000 civilian scientists, engineers and support personnel. NRL (